“I’m thinking about maybe having my tits done.”
—Rosie O’Neill, on The Trials of Rosie O’Neill, 1990.

(Photo: Ron Galella, Ltd. / WireImage)

“Jell-O-pudding-eating motherfucker.”
—Eddie Murphy, in Raw, first aired on HBO on 1992, recounting Richard Pryor’s take on Bill Cosby.

(Photo: Kevin Mazur / WireImage)

“You are always fucking with me.”
—Madonna, on The Late Show With David Letterman, 1994.

(Photo: 20th Century Fox / Everett Collection)

“Shit happens.”
—Mark Harmon, on a 1999 episode of Chicago Hope, uttering the word shit for the first time on network television.

(Photo: Comedy Central / Everett Collection)

“It Hits the Fan,”
A 2001 episode of South Park that used shit 162 times.

“He gotta lotta heart for a cocksucker,”
—Russell “Stringer” Bell, talking about Omar Little, in the first season of The Wire, 2002.

(Photo: Jim Smeal / WireImage)

“I Ain’t Dead Yet, Motherfucker,”
From a 2003 Richard Pryor special on Comedy Central, two years before he died.

Have you ever tried to get cow shit out of a Prada purse?”
—Nicole Richie, at the 2003 Billboard Music Awards.

“I Piss on You.”
—from a skit on Chappelle’s Show, 2003.

(Photo: Djamilla Rosa Cochran / WireImage)

“Fucking brilliant!”
—Bono, 2003 Golden Globes.

“The ‘C’ Word”
Episode of 30 Rock, 2007.

(Photo: Patrick McMullan )

“I’d like to have lips like [yours]. Then I wouldn’t have worked on my fucking personality.”
—Diane Keaton, to Diane Sawyer on Good Morning America, 2008.

(Photo: Patrick McMullan )

“I live in Georgia, okay? And I was asked to do a monologue called ‘cunt.’ ”
—Jane Fonda, discussing her role in The Vagina Monologues with Meredith Vieira, 2008.