GQ did a nice roundup with the creators of Lost, Fringe, Star Trek, and Transformers, "Geekdom's Counsel of Elders." It's worth reading as a whole, especially for Lost fans, as well as for illuminating bits of TV history like this exchange:

Bryan Burk: I also think with the shift in how television is now, it's possible to watch serialized shows on DVD, which you couldn't do twenty years ago, let alone 30 years ago. There are loyal viewers who watch it every week, but you can also wait and watch it all as a box set and still be in the loop as to what's going on in television. When we started Lost, doing serialized television was unacceptable. None of the shows were working, that were serialized. I remember vividly saying [to the network] that they'd be standalone episodes. The episodes will be serialized, but they'll also be standalone.
Damon Lindelof: We lied.

And this far more depressing one:

Roberto Orci: Networks don't want serialized.
Damon Lindelof: Yeah, serialized is still a dirty word.
J.J. Abrams: Literally—I was at a network pitch recently, and someone mentioned how the show we were discussing would be a standalone show, and there was applause in the room. Literally. They don't want shows that people have to invest that kind of time in, and make that kind of commitment to.

(I also loved when Orci wisecracked: "I hate serialization. And I'll tell you why next week.")