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K. Mikimoto invented the cultured pearl in 1893, and his spirit lives on in this Fifth Avenue shop. Cultured pearls—sometimes mixed with diamonds—are the store’s specialty.

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As an alternative to the traditional engagement ring, Mikimoto uses a pearl as the centerpiece and embellishes with diamonds or other gems. A simple gold or diamond band with a tiny pearl or a row of blue sapphires could serve as unconventional wedding bands.