Stay up late at Twelve Picardy Place, (from $215 per night), located in a Georgian townhouse that used to be an after-hours watering hole. The hotel’s stately exterior belies its ten guest rooms’ clean, modern look: oversize, black-and-white photography of Edinburgh screened onto walls, striped linens, and flooring in understated shades of gray. For an extra Jetsons-ian touch, go for one of the two Grand Master Suites, which have massage chairs, LCD flat-screens equipped with 3-D glasses, and enormous freestanding bathtubs. Head down to the clubby Steak restaurant for dinner, where exposed beams, gleaming hardwood floors, and industrial-chic overhead lighting set the stage; indulge in a shared Chateaubriand ($100), served from a classic steakhouse trolley, or try the slightly more affordable local Aberdeen Angus fillet ($48).
Go mod at The Glasshouse (from $280), a newly renovated boutique hotel within the 150-year old façade of the Lady Glenorchy church. The 65 striking guestrooms are filled with brightly colored Pop Art, chrome fixtures, and floor-to-ceiling windows. If you pony up for a suite, you’ll be able to take in views of the Scottish Parliament and Gothic governmental buildings that line nearby Calton Hill while sipping a complimentary carafe of Talisker single-malt Scotch whisky. Stay in for dinner and order the duo of Gressingham duck ($29) from the Glenorchy à la carte room service menu to enjoy on your private terrace.
Dive into la dolce vita at Hotel Missoni Edinburgh (from $207 per night), a stylish spot that the famed Italian fashion house opened on the Royal Mile in 2009. Rooms boast plush Missoni bed linens in signature zigzag stripes, chic, black-and-white Missoni robes, and colorful throw rugs, plus Missoni soaps in the silver-tiled bathrooms, each with an individual scent specifically designed for the hotel. Ride the wildly patterned elevators to the second floor to sample Missoni family favorites like tagliatelle all'emiliana at Cucina restaurant ($20), or sip a Bellini beneath Tom Dixon’s mirror-ball lights in the lobby-facing Bar Missoni ($13).