Orchard Street, Between Canal and Broome Streets
The Lower East Side’s art-fashion-nightlife nexus seeps into Chinatown.
16A Orchard St.; 917-470-9367
Trendy duds for both genders surrounded by country-club décor.
• The Fat Radish
17 Orchard St.; 212-300-4053
Greenmarket-driven comfort food and cocktails for the conspicuously good-looking.
30 Orchard St.; 212-608-6002
A gallery presenting large-scale installations and attitude to match.
• Scaramouche Gallery
52 Orchard St.; 212-228-2229
A teeny space touting on-the-cusp artists.
83½ Orchard St.; 917-769-2220
The sliver of a jewelry shop peddles oddities like pendants made from carved piano keys.
• Casa Mezcal
86 Orchard St.; 212-777-2600
A den of colored lights, Mezcal, and Oaxacan-style toasted grasshoppers.
87 Orchard St.; 212-334-3499
Dominican, Nicaraguan, and Ecuadoran stogies, and a haven in which to smoke them.
North 3rd Street, Between Berry Street and Kent Avenue
Every Williamsburg trope—from yoga to designer denim to fancy pickles—on two blocks.
• Cantina Royal
58 N. 3rd St.; 347-763-2938
La Superior’s just-launched higher-brow cousin stuffs tortillas with duck confit and octopus.
• Kula Brooklyn
85 N. 3rd St.; 347-463-9886
A yoga studio preaching both unisex flow and Yoga for Dudes.
• Brooklyn Denim Co.
85 N. 3rd St.; 718-782-2600
A former Adriano Goldschmied exec stocks 30 jeans brands, both cheap and wallet-busting.
• Brooklyn Art Library
103A N. 3rd St.; 718-388-7941
Currently showing off 10,000 sketchbooks by as many amateur and pro artists.
• Brooklyn Oenology Tasting Room
209 Wythe Ave.; 718-599-1259
Mix and match your own four-pour flights ($12 to $16) from nearby wineries.
242 Wythe Ave.; 347-227-8424
A Canadian-inspired gourmet shop shelving, naturally, locavore condiments.
Elizabeth Street, Between Prince and Houston Streets
The Nolita strip’s tenants turn over en masse.
• Thomas Sires
243 Elizabeth St.; 646-692-4472
High-end clothing and globally sourced giftables for the fairer sex.
• The Sock Hop
248 Elizabeth St.; 212-625-3105
Peacocky stockings, socks, and sunglasses.
248 Elizabeth St.; 212-343-7313
Gold-flecked Champagne flutes plus martini glasses equals no-brainer wedding gifts.
• Cynthia Vincent
253 Elizabeth St.; 646-707-3830
Between slouchy cocktail frocks and bright, flea-market-sourced baubles, the vibe is decidedly West Coast.
• Fonda Nolita
267 Elizabeth St.; 917-727-0179
A Nolita garage gone Baja, with heaping tacos served from a retrofitted VW bus.
• Billy’s Bakery
268 Elizabeth St.; 212-219-9956
The Magnolia rival’s third, icing-generous cupcake outpost.
• Love Adorned
269 Elizabeth St.; 212-431-5683
A favorite jewelry source, if you’re into wearing pebbles and feathers.
• Rag & Bone/JEAN
73 Houston St.; 212-777-2210
The British duo dedicate this outpost to denim and women’s shoes.
Reade Street, Between Church and Greenwich Streets
Finance and fashion meet cute and ride beach-cruisers on two Tribeca blocks.
• Color Me Mine
92 Reade St.; 212-374-1710
A two-month-old paint-your-own-ceramics studio.
• Ward III
111 Reade St.; 212-240-9194
The low-lit lounge slings $12 bespoke cocktails.
112 Reade St., second fl.; 212-406-1010
A manicured multitasker’s dream nail salon, equipped with Wi-Fi and iPads.
• Super Linda
109 W. Broadway; no phone yet
Ex–Beatrice co-owner Matt Abramcyk’s soon-to-debut 100-seat Latin bistro.
• Christina Lehr
139 Reade St.; no phone yet
Belgian-made knits both preppy (stripes!) and hippie (tie-dye!).
• Adeline Adeline
147 Reade St.; 212-227-1150
City bikes and all the accoutrements in loud colors.